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SMILES: FC1CCN(CCNC(=O)c2cccn3c2nc2cc4ccccc4cc2c3=O)C1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582326   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
DNA-directed RNA polymerase I subunit RPA1


(Homo sapiens (Human))		BDBM50582326
PNG
(CHEMBL5080196)
Show SMILES FC1CCN(CCNC(=O)c2cccn3c2nc2cc4ccccc4cc2c3=O)C1
PDB

KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.75E+3n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay

Citation and Details

Article DOI: 10.1021/acsmedchemlett.1c00660
BindingDB Entry DOI: 10.7270/Q2KW5KXW
More data for this
Ligand-Target Pair