null
SMILES: CN1CCCC1CNC(=O)c1cccn2c1nc1cc3ccccc3cc1c2=O
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
DNA-directed RNA polymerase I subunit RPA1 (Homo sapiens (Human)) | BDBM50582329 (CHEMBL5091418) | PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 3.94E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of RNA polymerase 1 in human A-375 assessed as RPA194 degradation measured after 4 hrs by Hoechst 33342 staining based assay | Citation and Details Article DOI: 10.1021/acsmedchemlett.1c00660 BindingDB Entry DOI: 10.7270/Q2KW5KXW | |||||||||||
More data for this Ligand-Target Pair |