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SMILES: [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN(C)C)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CC2)CC1)c1cccc(F)c1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50582737   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Menin


(Homo sapiens (Human))		BDBM50582737
PNG
(CHEMBL5076146)
Show SMILES [H][C@@]1(CCC[C@@H]1NC(=O)OC)[C@@](CN(C)C)(C1CCN(CC2CN(C2)c2ccc(cc2)S(=O)(=O)C2CC2)CC1)c1cccc(F)c1 |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.70n/an/an/an/an/an/a


TBA

Assay Description
Binding affinity to menin (unknown origin) incubated for 1 hr by fluorescence polarization-based competitive binding assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00789
BindingDB Entry DOI: 10.7270/Q2GX4GFD
More data for this
Ligand-Target Pair