null
SMILES: Cc1c(COc2ccc(CN[C@H](CO)C(O)=O)c(OCc3cncc(c3)C#N)n2)cccc1-c1ccccc1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Programmed cell death 1 ligand/protein 1 (Homo sapiens-Homo sapiens (Human)) | BDBM50582861 (CHEMBL5093056) | PDB UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 12 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of PD-1/PDL-1 (unknown origin) binding | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01409 BindingDB Entry DOI: 10.7270/Q22R3WJW | |||||||||||
More data for this Ligand-Target Pair |