null
SMILES: Fc1cnc(Nc2ccc(cn2)N2CCNCC2)nc1-c1ccc2nccnc2c1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase pim-1 (Homo sapiens (Human)) | BDBM50583157 (CHEMBL5082230) | PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 318 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of PIM1 (unknown origin) using 5FAM-ARKRRRHPSGPPTA peptide substrate incubated for 2 hrs by by electrophoretic mobility change analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02019 BindingDB Entry DOI: 10.7270/Q2D222HB | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Cyclin-dependent kinase 6 (Homo sapiens (Human)) | BDBM50583157 (CHEMBL5082230) | PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 118 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of CDK6 (unknown origin) by TR-FRET analysis | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02019 BindingDB Entry DOI: 10.7270/Q2D222HB | |||||||||||
More data for this Ligand-Target Pair |