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SMILES: Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H](Cc2ccc(O)cc2)C(O)=O)n1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583205   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Small conductance calcium-activated potassium channel protein 2


(Rattus norvegicus (Rat))		BDBM50583205
PNG
(CHEMBL5069418)
Show SMILES Cc1cc(C)n(n1)-c1nc(C)cc(N[C@@H](Cc2ccc(O)cc2)C(O)=O)n1 |r|
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a>1.00E+5n/an/an/an/a


TBA

Assay Description
Potentiation of rat KCa2.2a expressed in HEK293 cells at -90 mV holding potential measured at 1 to 2 days by patch clamp electrophysiology

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01473
BindingDB Entry DOI: 10.7270/Q28919R5
More data for this
Ligand-Target Pair