null

SMILES: CCNC(=N)NC(=O)Nc1c(CC)cccc1CC

InChI Key:

PDB links: 4 PDB IDs match this monomer.

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50583310   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of hERG expressed in HEK cells by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01565 BindingDB Entry DOI: 10.7270/Q2MG7TD0
					More data for this Ligand-Target Pair
Voltage-dependent L-type calcium channel subunit alpha-1C (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	8.35E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human Cav1.2 expressed in HEK cells by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01565 BindingDB Entry DOI: 10.7270/Q2MG7TD0
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00227 BindingDB Entry DOI: 10.7270/Q2RR238M
					More data for this Ligand-Target Pair
Cytochrome P450 3A4 (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of CYP3A4 in human liver microsomes pre-incubated for 30 min in presence of NADPH by LC-LS/MS analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01565 BindingDB Entry DOI: 10.7270/Q2MG7TD0
					More data for this Ligand-Target Pair
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00227 BindingDB Entry DOI: 10.7270/Q2RR238M
					More data for this Ligand-Target Pair
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human))	BDBM50583310 (CHEMBL5082711) Show SMILES CCNC(=N)NC(=O)Nc1c(CC)cccc1CC Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid PDB UniChem	Article PubMed	n/a	n/a	3.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of human Nav1.5 expressed in HEK cells by patch clamp method				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01565 BindingDB Entry DOI: 10.7270/Q2MG7TD0
					More data for this Ligand-Target Pair