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SMILES: CC(C)OC1CN(C1)C(=O)NC(C)c1ccc(cc1C)-c1ccnc(Nc2cnn(C)c2)n1

InChI Key:

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50583935   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Tyrosine-protein kinase BTK


(Homo sapiens (Human))		BDBM50583935
PNG
(CHEMBL5080657)
Show SMILES CC(C)OC1CN(C1)C(=O)NC(C)c1ccc(cc1C)-c1ccnc(Nc2cnn(C)c2)n1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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PC cid
PC sid
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Article
PubMed
n/an/a 12n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human BTK using fluorescein-labeled polyGAT peptide as substrate incubated for 30 mins by FRET assay

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c00926
BindingDB Entry DOI: 10.7270/Q23B641C
More data for this
Ligand-Target Pair