null
SMILES: CC(CO)CN(C)c1ncnc2[nH]cc(-c3cccc(Cl)c3)c12
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Serine/threonine-protein kinase 4 (Homo sapiens (Human)) | BDBM50583991 (CHEMBL5092052) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 38 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant N-terminal His6-tagged human STK4 (43 to 431 residues) expressed in Escherichia coli using myelin basic protein as substrat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 3 (Homo sapiens (Human)) | BDBM50583991 (CHEMBL5092052) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 58 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of recombinant N-terminal His6-tagged human STK3 (18 to 311 residues) expressed in Escherichia coli using myelin basic protein as substrat... | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Leucine-rich repeat serine/threonine-protein kinase 2 (Homo sapiens (Human)) | BDBM50583991 (CHEMBL5092052) | PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 7.14E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of K5 tracer from full length C-terminal NanoLuc fused human LRRK2 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 4 (Homo sapiens (Human)) | BDBM50583991 (CHEMBL5092052) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 444 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of K5 tracer from full length C-terminal NanoLuc fused human STK4 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Serine/threonine-protein kinase 3 (Homo sapiens (Human)) | BDBM50583991 (CHEMBL5092052) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | Article PubMed | n/a | n/a | 289 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Displacement of K5 tracer from full length C-terminal NanoLuc fused human STK3 expressed in HEK293T cells incubated for 2 hrs by NanoBRET assay | Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00804 BindingDB Entry DOI: 10.7270/Q2Q52TH8 | |||||||||||
More data for this Ligand-Target Pair |