null

SMILES: [H][C@]12CN([C@H](CN1C(=O)c1ncccc1[C@]2([H])c1cc2OCOc2c(OC)c1)C(=O)c1ccccc1)C(C)=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50584526   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-dependent translocase ABCB1 (Homo sapiens (Human))	BDBM50584526 (CHEMBL5086978) Show SMILES [H][C@]12CN([C@H](CN1C(=O)c1ncccc1[C@]2([H])c1cc2OCOc2c(OC)c1)C(=O)c1ccccc1)C(C)=O |r| Show InChI	PDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	280	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of P-glycoprotein overexpressed in human SW620/AD300 cells assessed as reversal of doxorubicin resistance by measuring doxorubicin IC50 at...				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c01989 BindingDB Entry DOI: 10.7270/Q2QZ2FV4
					More data for this Ligand-Target Pair