null

SMILES: [H][C@@]12[C@@H](C)OC(=O)[C@]1(O)CC(F)(F)[C@@H](CC)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50585036   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM50585036 (CHEMBL5094241) Show SMILES [H][C@@]12[C@@H](C)OC(=O)[C@]1(O)CC(F)(F)[C@@H](CC)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N |r| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Inhibition of [35S]MK-499 binding to hERG expressed in HEK293 cells				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02048 BindingDB Entry DOI: 10.7270/Q2514342
					More data for this Ligand-Target Pair
Proteinase-activated receptor 1 (Homo sapiens (Human))	BDBM50585036 (CHEMBL5094241) Show SMILES [H][C@@]12[C@@H](C)OC(=O)[C@]1(O)CC(F)(F)[C@@H](CC)[C@@H]2\C=C\c1ccc(cn1)-c1ccccc1C#N |r| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Antagonist activity at human PAR-1 expressed in HEK293 cells assessed as reduction in TRAP induced calcium signal at 3 uM by FLIPR analysis				Citation and Details Article DOI: 10.1021/acs.jmedchem.1c02048 BindingDB Entry DOI: 10.7270/Q2514342
					More data for this Ligand-Target Pair