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null

SMILES: [O-][N+](=O)CC(c1c([nH]c2ccccc12)-c1ccsc1)c1ccccc1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50586724
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50586724 (CHEMBL5082666) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	43	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Displacement of [3H]CP55940 from human CB1 receptor expressed in CHO-K1 cell membranes incubated for 60 mins by liquid scintillation spectrometry ana...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116421 BindingDB Entry DOI: 10.7270/Q2GT5S30
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50586724 (CHEMBL5082666) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	320	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as beta-arrestin 2 recruitment incubated for 90 mins by PathH...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116421 BindingDB Entry DOI: 10.7270/Q2GT5S30
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Mus musculus (Mouse))	BDBM50586724 (CHEMBL5082666) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	30	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of CB1 receptor in MF1 mouse vas deferens assessed as inhibition of AEA-induced electrically evoked vas deferens contr...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116421 BindingDB Entry DOI: 10.7270/Q2GT5S30
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50586724 (CHEMBL5082666) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	130	n/a	n/a	n/a	n/a
TBA					Assay Description Agonist activity at human CB1 receptor expressed in CHO cell membranes assessed as increase in [35S]GTPgammaS binding incubated for 30 mins by liquid...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116421 BindingDB Entry DOI: 10.7270/Q2GT5S30
TBA					More data for this Ligand-Target Pair
Cannabinoid receptor 1 (Homo sapiens (Human))	BDBM50586724 (CHEMBL5082666) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	Purchase MCE PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	87	n/a	n/a	n/a	n/a
TBA					Assay Description Positive allosteric modulation of human CB1 receptor expressed in CHO-K1 cells assessed as inhibition of forskolin-induced cAMP production incubated ...				Citation and Details Article DOI: 10.1016/j.bmc.2021.116421 BindingDB Entry DOI: 10.7270/Q2GT5S30
TBA					More data for this Ligand-Target Pair