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SMILES: C[C@H](Oc1cc(NC(=O)C(\C#N)=C(\C)O)c(F)cc1C(=O)Nc1c(Cl)cccc1Br)C(F)(F)F

InChI Key:

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50587011   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM50587011
PNG
(CHEMBL5091526)
Show SMILES C[C@H](Oc1cc(NC(=O)C(\C#N)=C(\C)O)c(F)cc1C(=O)Nc1c(Cl)cccc1Br)C(F)(F)F |r|
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PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.20n/an/an/an/an/an/a


TBA

Assay Description
Inhibition of human DHODH using dihydroorotate substrate preincubated for 30 mins followed by substrate addition by DCIP based microplate reader anal...

Citation and Details

Article DOI: 10.1021/acs.jmedchem.1c01711
BindingDB Entry DOI: 10.7270/Q2959NGP
More data for this
Ligand-Target Pair