null

SMILES: CCC(=O)N[C@H]1CC[C@@H](CC1)n1c2cc(Nc3ccc(N4CCN(C)CC4)c(C)c3)ccc2cc(-c2ccccc2Cl)c1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50599335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM50599335 (CHEMBL5194245) Show SMILES CCC(=O)N[C@H]1CC[C@@H](CC1)n1c2cc(Nc3ccc(N4CCN(C)CC4)c(C)c3)ccc2cc(-c2ccccc2Cl)c1=O |r,wU:5.4,wD:8.11,(4,-6.54,;2.66,-5.77,;2.66,-4.23,;4,-3.46,;1.33,-3.46,;1.33,-1.92,;-0,-1.15,;-0,.39,;1.33,1.16,;2.66,.39,;2.66,-1.15,;1.33,2.7,;-0,3.47,;-1.33,2.7,;-2.67,3.46,;-4,2.69,;-4,1.15,;-2.67,.38,;-2.67,-1.15,;-4,-1.92,;-4,-3.46,;-2.67,-4.24,;-2.67,-5.77,;-4,-6.55,;-4,-8.09,;-5.34,-5.78,;-5.34,-4.24,;-5.33,-1.16,;-6.66,-1.93,;-5.34,.38,;-2.67,5.01,;-1.33,5.78,;-0,5.01,;1.33,5.78,;2.66,5.01,;4,5.78,;4,7.32,;5.33,8.09,;6.66,7.31,;6.66,5.78,;5.34,5.01,;5.34,3.46,;2.66,3.47,;4,2.7,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	38	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details Article DOI: 10.1021/acs.jmedchem.1c00876 BindingDB Entry DOI: 10.7270/Q2QF8XXX
					More data for this Ligand-Target Pair