BDBM50739 7-(4-methylphenyl)-5-phenyl-4-pyrido[2,3-d]pyrimidinamine::7-(4-methylphenyl)-5-phenyl-pyrido[2,3-d]pyrimidin-4-amine::7-(4-methylphenyl)-5-phenylpyrido[2,3-d]pyrimidin-4-amine::MLS000858996::SMR000459175::[5-phenyl-7-(p-tolyl)pyrido[2,3-d]pyrimidin-4-yl]amine::cid_2817166
SMILES: Cc1ccc(cc1)-c1cc(-c2ccccc2)c2c(N)ncnc2n1
InChI Key: InChIKey=TYHSPMPGRFODKV-UHFFFAOYSA-N
Data: 3 IC50
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human)) | BDBM50739 (7-(4-methylphenyl)-5-phenyl-4-pyrido[2,3-d]pyrimid...) | PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 2.88E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
Emory University Molecular Libraries Screening Center Curated by PubChem BioAssay | Assay Description NIH Molecular Libraries Screening Centers Network [MLSCN] Emory Chemical Biology Discovery Center in MLSCN Assay provider: Nikolovska-Coleska, Univer... | PubChem Bioassay (2008) BindingDB Entry DOI: 10.7270/Q23X8539 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
nuclear receptor corepressor 2 isoform 2 (Homo sapiens (Human)) | BDBM50739 (7-(4-methylphenyl)-5-phenyl-4-pyrido[2,3-d]pyrimid...) | PDB MMDB B.MOAD GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 237 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q28914BQ | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
photoreceptor-specific nuclear receptor (Homo sapiens (Human)) | BDBM50739 (7-(4-methylphenyl)-5-phenyl-4-pyrido[2,3-d]pyrimid...) | PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet | Purchase PC cid PC sid UniChem Similars | PCBioAssay | n/a | n/a | 178 | n/a | n/a | n/a | n/a | n/a | n/a |
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay | Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center Affiliation: The Scripps Research Institute, TSRI Assay Provide... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2D21W22 | |||||||||||
More data for this Ligand-Target Pair |