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SMILES: Cc1csc(CN(CCc2nc3c4ccc5OC(F)(F)Oc5c4nc(N)n3n2)CC2CC2)n1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 508614   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Adenosine receptor A2a


(Homo sapiens (Human))		BDBM508614
PNG
(8-(2-{(cyclopropylmethyl)[(4- methyl-1,3-thiazol-2...)
Show SMILES Cc1csc(CN(CCc2nc3c4ccc5OC(F)(F)Oc5c4nc(N)n3n2)CC2CC2)n1
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
US Patent
 0.700n/an/an/an/an/an/an/an/a


TBA

Assay Description
The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...

Citation and Details

BindingDB Entry DOI: 10.7270/Q28S4T2C
More data for this
Ligand-Target Pair