null

SMILES: Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CCCC(F)(C3)C(F)(F)F)nn12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 508630   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Adenosine receptor A2a (Homo sapiens (Human))	BDBM508630 (US11046714, Example 72 | US11046714, Example 73) Show SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CCCC(F)(C3)C(F)(F)F)nn12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T2C
					More data for this Ligand-Target Pair
Adenosine receptor A2a (Homo sapiens (Human))	BDBM508630 (US11046714, Example 72 | US11046714, Example 73) Show SMILES Nc1nc2c3OC(F)(F)Oc3ccc2c2nc(CCN3CCCC(F)(C3)C(F)(F)F)nn12 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	0.900	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The following table shows representative data for the compounds of the Examples as A2a receptor antagonists as determined by a competition binding as...				Citation and Details BindingDB Entry DOI: 10.7270/Q28S4T2C
					More data for this Ligand-Target Pair