BDBM5115 N-(4-Isobutyl-5-isopropyl-3-methyl-1,3-thiazol-2(3H)-ylidene)-3-nitrobenzenesulfonamide::N-[(2Z)-3-methyl-4-(2-methylpropyl)-5-(propan-2-yl)-2,3-dihydro-1,3-thiazol-2-ylidene]-3-nitrobenzene-1-sulfonamide::thiazolidenebenzenesulfonamide deriv. 17h

SMILES: CC(C)Cc1c(s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n1C)C(C)C

InChI Key: InChIKey=VVTIEIUQNXGQMH-ZCXUNETKSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5115   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM5115 (N-(4-Isobutyl-5-isopropyl-3-methyl-1,3-thiazol-2(3...) Show SMILES CC(C)Cc1c(s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n1C)C(C)C Show InChI InChI=1S/C17H23N3O4S2/c1-11(2)9-15-16(12(3)4)25-17(19(15)5)18-26(23,24)14-8-6-7-13(10-14)20(21)22/h6-8,10-12H,9H2,1-5H3/b18-17-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (Y181C) (Human immunodeficiency virus type 1)	BDBM5115 (N-(4-Isobutyl-5-isopropyl-3-methyl-1,3-thiazol-2(3...) Show SMILES CC(C)Cc1c(s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n1C)C(C)C Show InChI InChI=1S/C17H23N3O4S2/c1-11(2)9-15-16(12(3)4)25-17(19(15)5)18-26(23,24)14-8-6-7-13(10-14)20(21)22/h6-8,10-12H,9H2,1-5H3/b18-17-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (K103N) (Human immunodeficiency virus type 1)	BDBM5115 (N-(4-Isobutyl-5-isopropyl-3-methyl-1,3-thiazol-2(3...) Show SMILES CC(C)Cc1c(s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n1C)C(C)C Show InChI InChI=1S/C17H23N3O4S2/c1-11(2)9-15-16(12(3)4)25-17(19(15)5)18-26(23,24)14-8-6-7-13(10-14)20(21)22/h6-8,10-12H,9H2,1-5H3/b18-17-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair