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SMILES: Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CCS(=O)(=O)c3ccc(cc3F)S(N)(=O)=O)CC2)C(F)(F)F)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 511557   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Carbonic anhydrase 2 (Homo sapiens (Human))	BDBM511557 (US11059794, Example 6.17 | tert-butyl 4-[2-(2-fluo...) Show SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CCS(=O)(=O)c3ccc(cc3F)S(N)(=O)=O)CC2)C(F)(F)F)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	7.10	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Human carbonic anhydrase II (hCA-II) inhibition was measured by an absorbance method using 4-nitrophenyl acetate (4-NPA) as its substrate. 4-NPA can ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K51
					More data for this Ligand-Target Pair
Ataxin-1 (Homo sapiens (Human))	BDBM511557 (US11059794, Example 6.17 | tert-butyl 4-[2-(2-fluo...) Show SMILES Cc1nnn(Cc2cc(ccc2CCC(=O)N2CCC(CCS(=O)(=O)c3ccc(cc3F)S(N)(=O)=O)CC2)C(F)(F)F)n1 Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description ATX inhibition was measured by a fluorescence quenching assay using a specifically labeled substrate analogue (MR121 substrate). To obtain this MR121...				Citation and Details BindingDB Entry DOI: 10.7270/Q2KW5K51
					More data for this Ligand-Target Pair