BDBM5121 3-methyl-2-[(3-nitrobenzene)sulfonamido]-5-(propan-2-yl)-2,3-dihydro-1,3-thiazole-4-carboxamide::4- and 5-substituted thiazolidene deriv. 19::5-Isopropyl-3-methyl-2-{[(3-nitrophenyl)sulfonyl]imino}-2,3-dihydro-1,3-thiazole-4-carboxamide

SMILES: CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C(N)=O

InChI Key: InChIKey=GHFIJZDKYNCSQG-PEZBUJJGSA-N

Data: 3 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 5121   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
HIV-1 Reverse Transcriptase (Human immunodeficiency virus type 1)	BDBM5121 (3-methyl-2-[(3-nitrobenzene)sulfonamido]-5-(propan...) Show SMILES CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C(N)=O Show InChI InChI=1S/C14H16N4O5S2/c1-8(2)12-11(13(15)19)17(3)14(24-12)16-25(22,23)10-6-4-5-9(7-10)18(20)21/h4-8H,1-3H3,(H2,15,19)/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (Y181C) (Human immunodeficiency virus type 1)	BDBM5121 (3-methyl-2-[(3-nitrobenzene)sulfonamido]-5-(propan...) Show SMILES CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C(N)=O Show InChI InChI=1S/C14H16N4O5S2/c1-8(2)12-11(13(15)19)17(3)14(24-12)16-25(22,23)10-6-4-5-9(7-10)18(20)21/h4-8H,1-3H3,(H2,15,19)/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>2.50E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair
HIV-1 Reverse Transcriptase Mutant (K103N) (Human immunodeficiency virus type 1)	BDBM5121 (3-methyl-2-[(3-nitrobenzene)sulfonamido]-5-(propan...) Show SMILES CC(C)c1s\c(=N/S(=O)(=O)c2cccc(c2)[N+]([O-])=O)n(C)c1C(N)=O Show InChI InChI=1S/C14H16N4O5S2/c1-8(2)12-11(13(15)19)17(3)14(24-12)16-25(22,23)10-6-4-5-9(7-10)18(20)21/h4-8H,1-3H3,(H2,15,19)/b16-14-	PDB MMDB B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Yamanouchi Pharmaceutical Co. Ltd					Assay Description The IC50 of reverse transcriptase is the concentration that inhibits 50% of recombinant HIV-1 RT RNA-directed DNA polymerase activity in vitro.				Bioorg Med Chem 12: 6171-82 (2004) Article DOI: 10.1016/j.bmc.2004.08.050 BindingDB Entry DOI: 10.7270/Q23R0R24
					More data for this Ligand-Target Pair