null

SMILES: CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc4CN(CCc4n3)C(=O)CO)ncc2F)C11CCCC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 513486   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Cyclin-dependent kinase 6/G1/S-specific cyclin-D3 (Homo sapiens (Human))	BDBM513486 (1-(2-((5-fluoro-4-(7′-fluoro-2′-methyl...) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc4CN(CCc4n3)C(=O)CO)ncc2F)C11CCCC1 |t:1| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair
Cyclin-dependent kinase/G1/S-specific cyclin- 2 (Homo sapiens (Human))	BDBM513486 (1-(2-((5-fluoro-4-(7′-fluoro-2′-methyl...) Show SMILES CC1=Nc2c(cc(cc2F)-c2nc(Nc3ccc4CN(CCc4n3)C(=O)CO)ncc2F)C11CCCC1 |t:1| Show InChI	PDB UniProtKB/SwissProt antibodypedia antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	162	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description 1.2.2 Preparation of kinase solution: Kinase solutions having the concentrations required for each reaction system were prepared from 100 ng/...				Citation and Details BindingDB Entry DOI: 10.7270/Q2H13552
					More data for this Ligand-Target Pair