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SMILES: OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 515798   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM515798 (US11053225, Compound 100) Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:23.25,26.32,(1.73,-9.37,;.83,-8.12,;1.45,-6.72,;.55,-5.47,;1.02,-4.01,;-.22,-3.1,;-1.47,-4.01,;-.99,-5.47,;-.22,-1.56,;-1.56,-.79,;-1.56,.75,;-.22,1.52,;-.22,3.06,;-1.56,3.83,;-1.56,5.37,;-2.89,6.14,;-4.22,5.37,;-4.22,3.83,;-5.56,3.06,;-2.89,3.06,;1.11,.75,;1.11,-.79,;2.45,-1.56,;3.78,-.79,;3.78,.75,;5.11,1.52,;6.45,.75,;6.45,-.79,;5.11,-1.56,;7.78,1.52,;9.11,.75,;9.11,-.79,;10.45,1.52,;11.78,2.29,;11.22,.19,;9.68,2.85,)| Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.900	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM515798 (US11053225, Compound 100) Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:23.25,26.32,(1.73,-9.37,;.83,-8.12,;1.45,-6.72,;.55,-5.47,;1.02,-4.01,;-.22,-3.1,;-1.47,-4.01,;-.99,-5.47,;-.22,-1.56,;-1.56,-.79,;-1.56,.75,;-.22,1.52,;-.22,3.06,;-1.56,3.83,;-1.56,5.37,;-2.89,6.14,;-4.22,5.37,;-4.22,3.83,;-5.56,3.06,;-2.89,3.06,;1.11,.75,;1.11,-.79,;2.45,-1.56,;3.78,-.79,;3.78,.75,;5.11,1.52,;6.45,.75,;6.45,-.79,;5.11,-1.56,;7.78,1.52,;9.11,.75,;9.11,-.79,;10.45,1.52,;11.78,2.29,;11.22,.19,;9.68,2.85,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	0.910	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM515798 (US11053225, Compound 100) Show SMILES OCCn1cc(cn1)-c1cnc(Nc2cccc(Cl)c2)nc1N[C@@H]1CC[C@@H](CC1)NC(=O)C(F)(F)F |r,wD:23.25,26.32,(1.73,-9.37,;.83,-8.12,;1.45,-6.72,;.55,-5.47,;1.02,-4.01,;-.22,-3.1,;-1.47,-4.01,;-.99,-5.47,;-.22,-1.56,;-1.56,-.79,;-1.56,.75,;-.22,1.52,;-.22,3.06,;-1.56,3.83,;-1.56,5.37,;-2.89,6.14,;-4.22,5.37,;-4.22,3.83,;-5.56,3.06,;-2.89,3.06,;1.11,.75,;1.11,-.79,;2.45,-1.56,;3.78,-.79,;3.78,.75,;5.11,1.52,;6.45,.75,;6.45,-.79,;5.11,-1.56,;7.78,1.52,;9.11,.75,;9.11,-.79,;10.45,1.52,;11.78,2.29,;11.22,.19,;9.68,2.85,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	32	n/a	n/a	n/a	n/a	n/a	n/a
TBA									Citation and Details
					More data for this Ligand-Target Pair