BindingDB PrimarySearch

null

SMILES: C[C@H](CO)Nc1n[nH]c2nccc(Oc3ccc(NC(=O)c4cn(C(C)C)c(=O)n(-c5ccc(F)c(F)c5)c4=O)cc3F)c12

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 517022
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Hepatocyte growth factor receptor [D1228N] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [F1200I] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	45.8	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.90	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230H] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [D1228H] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	4	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	4.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.63E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.30	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [1-13,15-1390] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3.40	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230S] (Homo sapiens (Human))	BDBM517022 ((R)-3-(3,4- difluorophenyl)-N-(3- fluoro-4-((3-((1...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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