BindingDB PrimarySearch

null

SMILES: CCn1cc(C(=O)Nc2ccc(Oc3ccnc4[nH]nc(N[C@@H](C)COC)c34)c(F)c2)c(=O)n(-c2ccc(F)cc2)c1=O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 517078
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Tyrosine-protein kinase receptor UFO (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase Mer (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3.10E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Tyrosine-protein kinase receptor TYRO3 (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.22E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.20	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [1-13,15-1390] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.60	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230S] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [D1228N] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.10	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [F1200I] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [L1195V] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	22	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230C] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	1.70	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [Y1230H] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	2.30	n/a	n/a	n/a	n/a	n/a	n/a
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Hepatocyte growth factor receptor [D1228H] (Homo sapiens (Human))	BDBM517078 ((S)-1-ethyl-N-(3-fluoro- 4-((3-((1- methoxypropan-...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	n/a	n/a	3.5	n/a	n/a	n/a	n/a	n/a	n/a
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