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SMILES: Fc1ccc(cc1)-n1nc(-c2ccccc2Cl)c2ccc(cc12)C(=O)NC1CC(=O)NC1=O

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 517230   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Diacylglycerol O-acyltransferase 2


(Homo sapiens (Human))		BDBM517230
PNG
(3-(2-chlorophenyl)-N-(2,5- dioxopyrrolidin-3-yl)-1...)
Show SMILES Fc1ccc(cc1)-n1nc(-c2ccccc2Cl)c2ccc(cc12)C(=O)NC1CC(=O)NC1=O
Reactome pathway
KEGG

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 669n/an/an/an/an/an/a


TBA

Assay Description
DGAT2 activity was determined by measuring the amount of enzymatic product triolein (1,2,3-Tri(cis-9-octadecenoyl)glycerol) using the membrane prep m...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2ZP497K
More data for this
Ligand-Target Pair