null

SMILES: COC(=O)C1=C(CN2CCN3[C@H](CN(CC#Cc4c(C)cc(cc4C)C#N)C3=O)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520014   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Large envelope protein (Hepatitis B virus)	BDBM520014 (US11142527, Example 48) Show SMILES COC(=O)C1=C(CN2CCN3[C@H](CN(CC#Cc4c(C)cc(cc4C)C#N)C3=O)C2)NC(=N[C@H]1c1ccc(F)cc1Cl)c1nccs1 |r,c:4,34| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	n/a	n/a	6.30	n/a	n/a	n/a	n/a
TBA					Assay Description 8000 HepG 2.2.15 cells per well were seeded into a 96-well plate, the plate was cultured at 37° C. and 5% CO2 for 3 days till the cells grew to full ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2RV0RVC
					More data for this Ligand-Target Pair