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SMILES: Clc1ccc2c(CCCC22COc3ccc(cc3N(CC3CCC3)C2)S(=O)(=O)NC(=O)N2CCCC2)c1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520307   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Induced myeloid leukemia cell differentiation protein Mcl-1


(Homo sapiens (Human))		BDBM520307
PNG
(N-[6′-Chloro-5-(cyclobutylmethyl)spiro[2,4-d...)
Show SMILES Clc1ccc2c(CCCC22COc3ccc(cc3N(CC3CCC3)C2)S(=O)(=O)NC(=O)N2CCCC2)c1
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
 6n/an/an/an/an/an/an/an/a


TBA

Assay Description
The assay was carried out in black half-area 96-well NBS plate (Corning), containing 15 nM of MCL-1 (BPS Bioscience), 5 nM of FITC-Bim and 3-fold ser...

Citation and Details

BindingDB Entry DOI: 10.7270/Q26W9F7C
More data for this
Ligand-Target Pair