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SMILES: CN(C)Cc1cccc(c1)-c1c(F)c(F)c(-c2cc(C(O)=O)c3n(C)nnc3c2)c(F)c1F

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 520634   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dihydroorotate dehydrogenase (quinone), mitochondrial


(Homo sapiens (Human))		BDBM520634
PNG
(5-(3'-((dimethylamino)methyl)-2,3,5,6-tetrafluoro-...)
Show SMILES CN(C)Cc1cccc(c1)-c1c(F)c(F)c(-c2cc(C(O)=O)c3n(C)nnc3c2)c(F)c1F
PDB
MMDB

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TBA

Assay Description
The DHODH activity assay is a coupled enzyme assay in which oxidation of DHO and subsequent reduction of ubiquinone are stoichiometrically equivalent...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2348PJD
More data for this
Ligand-Target Pair