null

SMILES: Cn1cc(Nc2nc(N3CC4CN(CC4C3)C(=O)C=C)c(F)c3CNC(=O)c23)cn1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 521889   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Epidermal growth factor receptor (Homo sapiens (Human))	BDBM521889 (US11155546, Compound G-76) Show SMILES Cn1cc(Nc2nc(N3CC4CN(CC4C3)C(=O)C=C)c(F)c3CNC(=O)c23)cn1 Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.37E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description EGFR: The working concentration of each component in 10 μl wild-type EGFR kinase reaction system was: 10 μM ATP, 0.8 ng/μl wild-type E...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89TC
					More data for this Ligand-Target Pair
Tyrosine-protein kinase BTK (Homo sapiens (Human))	BDBM521889 (US11155546, Compound G-76) Show SMILES Cn1cc(Nc2nc(N3CC4CN(CC4C3)C(=O)C=C)c(F)c3CNC(=O)c23)cn1 Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description BTK: The compound was predissolved in 100% DMSO. 10 mM drug stock solution was obtained by dissolution at room temperature and then serially diluted ...				Citation and Details BindingDB Entry DOI: 10.7270/Q23X89TC
					More data for this Ligand-Target Pair