BindingDB PrimarySearch

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SMILES: CCN1C(=O)Cc2cc(ccc12)-c1cncc(c1)-c1ccc(=O)n(c1)C(C)C

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 522112
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Activin receptor type-1 [172-499] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1A [198-525] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	620	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 53: The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were g...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
Bone morphogenetic protein receptor type-1B [168-495] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	490	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
Serine/threonine-protein kinase receptor R3 [166-493] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
TGF-beta receptor type-1 [162-503] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	2.50E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair
Activin receptor type-1 [172-499,R206H] (Homo sapiens (Human))	BDBM522112 (US11160797, Example 20) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Example 54:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 9 ul. Dose-response curves were ge...				Citation and Details BindingDB Entry DOI: 10.7270/Q2M048M3
TBA					More data for this Ligand-Target Pair