BDBM52474 2-[2,5-Dimethyl-3-(2,4,6-trioxo-tetrahydro-pyrimidin-5-ylidenemethyl)-pyrrol-1-yl]-4,5-dimethyl-thiophene-3-carbonitrile::2-[2,5-dimethyl-3-[(2,4,6-triketohexahydropyrimidin-5-ylidene)methyl]pyrrol-1-yl]-4,5-dimethyl-thiophene-3-carbonitrile::2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]-1-pyrrolyl]-4,5-dimethyl-3-thiophenecarbonitrile::2-[2,5-dimethyl-3-[(2,4,6-trioxo-1,3-diazinan-5-ylidene)methyl]pyrrol-1-yl]-4,5-dimethylthiophene-3-carbonitrile::2-[2,5-dimethyl-3-[[2,4,6-tris(oxidanylidene)-1,3-diazinan-5-ylidene]methyl]pyrrol-1-yl]-4,5-dimethyl-thiophene-3-carbonitrile::MLS000591328::SMR000218936::cid_1930867

SMILES: Cc1sc(c(C#N)c1C)-n1c(C)cc(C=C2C(=O)NC(=O)NC2=O)c1C

InChI Key: InChIKey=ULYMHXZNQJXOGF-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 52474   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
POsterior Segregation (Caenorhabditis elegans)	BDBM52474 (2-[2,5-Dimethyl-3-(2,4,6-trioxo-tetrahydro-pyrimid...) Show SMILES Cc1sc(c(C#N)c1C)-n1c(C)cc(C=C2C(=O)NC(=O)NC2=O)c1C |(3.08,4.58,;4.54,4.1,;5.02,2.64,;6.56,2.64,;7.04,4.1,;8.5,4.58,;9.97,5.06,;5.79,5.01,;5.79,6.55,;7.47,1.39,;9.01,1.39,;9.91,2.64,;9.48,-.07,;8.24,-.98,;8.24,-2.52,;9.57,-3.29,;9.57,-4.83,;8.24,-5.6,;10.9,-5.6,;12.24,-4.83,;13.57,-5.6,;12.24,-3.29,;10.9,-2.52,;10.9,-.98,;6.99,-.07,;5.53,-.55,)| Show InChI InChI=1S/C18H16N4O3S/c1-8-5-12(6-13-15(23)20-18(25)21-16(13)24)10(3)22(8)17-14(7-19)9(2)11(4)26-17/h5-6H,1-4H3,(H2,20,21,23,24,25)	PDB KEGG UniProtKB/TrEMBL GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q28G8J4C
					More data for this Ligand-Target Pair
Protein LANA1 (Human herpesvirus 8)	BDBM52474 (2-[2,5-Dimethyl-3-(2,4,6-trioxo-tetrahydro-pyrimid...) Show SMILES Cc1sc(c(C#N)c1C)-n1c(C)cc(C=C2C(=O)NC(=O)NC2=O)c1C |(3.08,4.58,;4.54,4.1,;5.02,2.64,;6.56,2.64,;7.04,4.1,;8.5,4.58,;9.97,5.06,;5.79,5.01,;5.79,6.55,;7.47,1.39,;9.01,1.39,;9.91,2.64,;9.48,-.07,;8.24,-.98,;8.24,-2.52,;9.57,-3.29,;9.57,-4.83,;8.24,-5.6,;10.9,-5.6,;12.24,-4.83,;13.57,-5.6,;12.24,-3.29,;10.9,-2.52,;10.9,-.98,;6.99,-.07,;5.53,-.55,)| Show InChI InChI=1S/C18H16N4O3S/c1-8-5-12(6-13-15(23)20-18(25)21-16(13)24)10(3)22(8)17-14(7-19)9(2)11(4)26-17/h5-6H,1-4H3,(H2,20,21,23,24,25)	PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	>7.50E+4	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Primary Collaborators: Kenneth Kaye,Brigham & Womens,Boston MA,kkaye@rics.bwh.harvard.edu,617-525-4256 Chantal Beauchemin,Brigham & Womens,Boston MA,...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2HH6HHN
					More data for this Ligand-Target Pair
Zinc finger protein mex-5 (Caenorhabditis elegans)	BDBM52474 (2-[2,5-Dimethyl-3-(2,4,6-trioxo-tetrahydro-pyrimid...) Show SMILES Cc1sc(c(C#N)c1C)-n1c(C)cc(C=C2C(=O)NC(=O)NC2=O)c1C |(3.08,4.58,;4.54,4.1,;5.02,2.64,;6.56,2.64,;7.04,4.1,;8.5,4.58,;9.97,5.06,;5.79,5.01,;5.79,6.55,;7.47,1.39,;9.01,1.39,;9.91,2.64,;9.48,-.07,;8.24,-.98,;8.24,-2.52,;9.57,-3.29,;9.57,-4.83,;8.24,-5.6,;10.9,-5.6,;12.24,-4.83,;13.57,-5.6,;12.24,-3.29,;10.9,-2.52,;10.9,-.98,;6.99,-.07,;5.53,-.55,)| Show InChI InChI=1S/C18H16N4O3S/c1-8-5-12(6-13-15(23)20-18(25)21-16(13)24)10(3)22(8)17-14(7-19)9(2)11(4)26-17/h5-6H,1-4H3,(H2,20,21,23,24,25)	KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+5	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Broad Institute: MLPCN maternal gene expression Project ID: 2024 Keywords: Zinc finger, C. elegans, maternal gene expression, RNA-protein interac...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D798VP
					More data for this Ligand-Target Pair