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null

SMILES: FC(F)c1cc(no1)C(=O)N[C@@H](CC12CC(C1)C2)C(=O)NN(C[C@@H]1CCNC1=O)C(=O)[C@H](F)Cl

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 525251
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Replicase polyprotein 1ab (HCoV-OC43)	BDBM525251 (N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...) Show SMILES Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022043374	n/a	n/a	17	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the HCoV-OC433CLpro assay, 2 μL of 0.02 μM recombinant HCoV-OC433CL protease were mixed with serial dilutions of each comp...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SF30BV
TBA					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM525251 (N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...) Show SMILES Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022043374	n/a	n/a	24	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the SARS-CoV-2 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV-2 3CL protease were mixed with serial dilutions of each c...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SF30BV
TBA					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (HCoV-229E)	BDBM525251 (N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022043374	n/a	n/a	28	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the HCoV-229E 3CLpro assay, 2 μL of 0.02 μM recombinant HCoV-229E 3CL protease were mixed with serial dilutions of each com...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SF30BV
TBA					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM525251 (N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...) Show SMILES Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022043374	n/a	n/a	31	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the SARS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant SARS-CoV 3CL protease were mixed with serial dilutions of each compo...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SF30BV
TBA					More data for this Ligand-Target Pair
Orf1a protein (MERS-CoV)	BDBM525251 (N-[(1S)-2-[2-[(2R)-2-chloro-2-fluoro-acetyl]-2-[[(...) Show SMILES Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	WIPO WO2022043374	n/a	n/a	94	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description For the MERS-CoV 3CLpro assay, 2 μL of 0.02 μM recombinant MERS-CoV 3CL protease were mixed with serial dilutions of each compo...				Citation and Details BindingDB Entry DOI: 10.7270/Q2SF30BV
TBA					More data for this Ligand-Target Pair