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SMILES: Clc1cc(ccc1N[C@@H]1CCc2ccccc12)S(=O)(=O)Nc1ncns1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 525928   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kcal/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sodium channel protein type 8 subunit alpha


(Homo sapiens (Human))
BDBM525928
PNG
((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...)
Show SMILES Clc1cc(ccc1N[C@@H]1CCc2ccccc12)S(=O)(=O)Nc1ncns1 |r|
PDB

Reactome pathway
KEGG

UniProtKB/SwissProt

DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 839n/an/an/an/an/an/a


TBA

Assay Description
This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QF8X18
More data for this
Ligand-Target Pair
Sodium channel protein type 1 subunit alpha


(Homo sapiens (Human))
BDBM525928
PNG
((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...)
Show SMILES Clc1cc(ccc1N[C@@H]1CCc2ccccc12)S(=O)(=O)Nc1ncns1 |r|
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 301n/an/an/an/an/an/a


TBA

Assay Description
This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QF8X18
More data for this
Ligand-Target Pair
Sodium channel protein type 5 subunit alpha


(Homo sapiens (Human))
BDBM525928
PNG
((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...)
Show SMILES Clc1cc(ccc1N[C@@H]1CCc2ccccc12)S(=O)(=O)Nc1ncns1 |r|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 8.69E+3n/an/an/an/an/an/a


TBA

Assay Description
This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which...


Citation and Details

BindingDB Entry DOI: 10.7270/Q2QF8X18
More data for this
Ligand-Target Pair