null
SMILES: Clc1cc(ccc1N[C@@H]1CCc2ccccc12)S(=O)(=O)Nc1ncns1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Sodium channel protein type 8 subunit alpha (Homo sapiens (Human)) | BDBM525928 ((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 839 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QF8X18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 1 subunit alpha (Homo sapiens (Human)) | BDBM525928 ((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 301 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QF8X18 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Sodium channel protein type 5 subunit alpha (Homo sapiens (Human)) | BDBM525928 ((R)-3-chloro-4-((2,3-dihydro-1H-inden-1-yl)amino)-...) | PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 8.69E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description This sodium influx assay employs the use of the cell permeable, sodium sensitive dye ANG2 to quantify sodium ion influx through sodium channels which... | Citation and Details BindingDB Entry DOI: 10.7270/Q2QF8X18 | |||||||||||
More data for this Ligand-Target Pair |