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SMILES: Clc1ccc(OCCCc2nn3c([nH]c4ccccc4c3=O)c2C#N)cc1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 528579   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Dynein light chain 2, cytoplasmic


(Human)		BDBM528579
PNG
(US11192893, Example 29)
Show SMILES Clc1ccc(OCCCc2nn3c([nH]c4ccccc4c3=O)c2C#N)cc1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 730n/an/an/an/an/an/a


TBA

Assay Description
Compounds were tested employing a microtubule gliding assay, a standard biochemical assay for motor proteins. The first set of studies focused on hum...

Citation and Details

BindingDB Entry DOI: 10.7270/Q22J6G18
More data for this
Ligand-Target Pair