null
SMILES: CC(C)c1cn(-c2ccccc2C)c(=O)c2cc(F)c(cc12)-c1nc(CO)n(C)n1
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human)) | BDBM530437 (7-Fluoro-6-(5-(hydroxymethyl)-1-methyl-1H-1,2,4-tr...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022070068 | n/a | n/a | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th... | Citation and Details BindingDB Entry DOI: 10.7270/Q2GM8BGM | |||||||||||
More data for this Ligand-Target Pair |