null
SMILES: C[C@@H](O)c1nn(cc1C)-c1cc(O[C@@H](C)C(F)(F)F)c(cc1F)C(=O)Nc1c(C)n[nH]c1Cl
InChI Key:
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Dihydroorotate dehydrogenase (quinone), mitochondrial (Homo sapiens (Human)) | BDBM530461 (N-(5-Chloro-3-methyl-1H-pyrazol-4-yl)-5-fluoro-4-(...) | PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem | WIPO WO2022070069 | n/a | n/a | 0.220 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description To detect DHODH enzyme activities, dichloroindophenol (DCIP) is added as the final electron acceptor in the assay. DCIP can accept electrons from th... | Citation and Details BindingDB Entry DOI: 10.7270/Q2BV7KSB | |||||||||||
More data for this Ligand-Target Pair |