null

SMILES: NS(=O)(=O)c1c(ccc(N2CCC(CF)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 530957   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Metallo-beta-lactamase type 2 (Klebsiella pneumoniae)	BDBM530957 (4-[4- (fluoromethyl)piperidin-1- yl]-N1-[(3R)-pyrr...) Show SMILES NS(=O)(=O)c1c(ccc(N2CCC(CF)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN19BS
					More data for this Ligand-Target Pair
Metallo-beta-lactamase VIM-2 (Pseudomonas aeruginosa (g-Proteobacteria))	BDBM530957 (4-[4- (fluoromethyl)piperidin-1- yl]-N1-[(3R)-pyrr...) Show SMILES NS(=O)(=O)c1c(ccc(N2CCC(CF)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.660	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN19BS
					More data for this Ligand-Target Pair
VIM-1 metallo-beta-lactamase (Klebsiella pneumoniae)	BDBM530957 (4-[4- (fluoromethyl)piperidin-1- yl]-N1-[(3R)-pyrr...) Show SMILES NS(=O)(=O)c1c(ccc(N2CCC(CF)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB UniProtKB/TrEMBL GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.210	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN19BS
					More data for this Ligand-Target Pair
Beta-lactamase (Pseudomonas aeruginosa)	BDBM530957 (4-[4- (fluoromethyl)piperidin-1- yl]-N1-[(3R)-pyrr...) Show SMILES NS(=O)(=O)c1c(ccc(N2CCC(CF)CC2)c1-c1nnn[nH]1)S(=O)(=O)N[C@@H]1CCNC1 |r| Show InChI	PDB MMDB UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.610	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The Class B enzyme activities were measured in the presence of the test inhibitor in a fluorescence assay against a commercially available substrate ...				Citation and Details BindingDB Entry DOI: 10.7270/Q2FN19BS
					More data for this Ligand-Target Pair