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SMILES: Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)[C@@H](O)[C@H]1O

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 533501   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Replicase polyprotein 1ab (Human SARS coronavirus (SARS-CoV) (Severe acute re...)	BDBM533501 (jm2c00120, Compound 2) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)[C@@H](O)[C@H]1O Show InChI	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	7.60E+3	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00120 BindingDB Entry DOI: 10.7270/Q21839PH
					More data for this Ligand-Target Pair
Replicase polyprotein 1ab (2019-nCoV)	BDBM533501 (jm2c00120, Compound 2) Show SMILES Nc1ncnc2n(cnc12)[C@@H]1O[C@H](CNS(=O)(=O)c2ccc(cc2)[N+]([O-])=O)[C@@H](O)[C@H]1O Show InChI	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.41E+4	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The transfer of tritiated methyl from [3H] SAM onto RNA substrate was monitored by filter-binding assay, performed according to the method described ...				Citation and Details Article DOI: 10.1021/acs.jmedchem.2c00120 BindingDB Entry DOI: 10.7270/Q21839PH
					More data for this Ligand-Target Pair