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SMILES: COc1cccc(c1)C(=O)N[C@@H](CC1CC1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NC1CC1

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 535882   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Calpain-1 catalytic subunit


(Homo sapiens (Human))		BDBM535882
PNG
(US11242312, Example 3)
Show SMILES COc1cccc(c1)C(=O)N[C@@H](CC1CC1)C(=O)NC(Cc1ccccc1)C(=O)C(=O)NC1CC1 |r|
PDB
MMDB

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PC cid
PC sid
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US Patent
n/an/a 0.00800n/an/an/an/an/an/a


TBA

Assay Description
Activity of Calpain 1 was measured by using Calpain-Glo Protease kit from Promega. Assays were run in 384-well black plates with clear bottom. 5 _...

Citation and Details

BindingDB Entry DOI: 10.7270/Q27P92KJ
More data for this
Ligand-Target Pair