Found 5 hits for monomerid = 536922 Target/Host
(Institution) | Ligand | Target/Host
Links | Ligand
Links | Trg + Lig
Links | Ki
nM | ΔG°
kcal/mole | IC50
nM | Kd
nM | EC50/IC50
nM | koff
s-1 | kon
M-1s-1 | pH | Temp
°C |
|---|
Epidermal growth factor receptor [1-773,'NPH',774-1210]
(Homo sapiens (Human)) | BDBM536922
(US11896597, Compound 47)Show SMILES CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(c(F)c2)S(N)(=O)=O)c1C1CC1)-c1ccc(F)c(c1)-c1ccc(C)cc1 | PDB
MMDB
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet 
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 5.60 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| |
J Med Chem 50: 4728-45 (2007)
BindingDB Entry DOI: 10.7270/Q2S75JMR |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [1-769,'ASV',770-1210]
(Homo sapiens (Human)) | BDBM536922
(US11896597, Compound 47)Show SMILES CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(c(F)c2)S(N)(=O)=O)c1C1CC1)-c1ccc(F)c(c1)-c1ccc(C)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 10.1 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| |
J Med Chem 50: 4728-45 (2007)
BindingDB Entry DOI: 10.7270/Q2S75JMR |
More data for this
Ligand-Target Pair | |
egfr wt
(Homo sapiens (Human)) | BDBM536922
(US11896597, Compound 47)Show SMILES CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(c(F)c2)S(N)(=O)=O)c1C1CC1)-c1ccc(F)c(c1)-c1ccc(C)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
antibodypedia
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 23.8 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| |
J Med Chem 50: 4728-45 (2007)
BindingDB Entry DOI: 10.7270/Q2S75JMR |
More data for this
Ligand-Target Pair | |
Receptor tyrosine-protein kinase erbB-2 [1-775,'YVMA',776-1255]
(Homo sapiens (Human)) | BDBM536922
(US11896597, Compound 47)Show SMILES CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(c(F)c2)S(N)(=O)=O)c1C1CC1)-c1ccc(F)c(c1)-c1ccc(C)cc1 | PDB
MMDB
NCI pathway
Reactome pathway
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 4.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| |
J Med Chem 50: 4728-45 (2007)
BindingDB Entry DOI: 10.7270/Q2S75JMR |
More data for this
Ligand-Target Pair | |
Epidermal growth factor receptor [T790M,L858R]
(Homo sapiens (Human)) | BDBM536922
(US11896597, Compound 47)Show SMILES CCOC(=O)c1csc(n1)-n1nc(c(Cc2ccc(c(F)c2)S(N)(=O)=O)c1C1CC1)-c1ccc(F)c(c1)-c1ccc(C)cc1 | PDB
MMDB
KEGG
UniProtKB/SwissProt
B.MOAD
DrugBank
GoogleScholar
AffyNet
| PC cid
PC sid
UniChem
| US Patent
| n/a | n/a | 0.300 | n/a | n/a | n/a | n/a | n/a | n/a |
Wyeth Research
| |
J Med Chem 50: 4728-45 (2007)
BindingDB Entry DOI: 10.7270/Q2S75JMR |
More data for this
Ligand-Target Pair | |
Search and Browse
