BDBM54207 MLS000538647::N-[4-(3,4-dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]-1-methyl-4-nitro-pyrazole-3-carboxamide::N-[4-(3,4-dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]-1-methyl-4-nitropyrazole-3-carboxamide::N-[4-(3,4-dimethylphenyl)-5-methyl-1,3-thiazol-2-yl]-4-nitro-1-methyl-1H-pyrazole-3-carboxamide::N-[4-(3,4-dimethylphenyl)-5-methyl-2-thiazolyl]-1-methyl-4-nitro-3-pyrazolecarboxamide::N-[4-(3,4-dimethylphenyl)-5-methyl-thiazol-2-yl]-1-methyl-4-nitro-pyrazole-3-carboxamide::SMR000160112::cid_998879

SMILES: Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1

InChI Key: InChIKey=SSVYZBWWFLPCPS-UHFFFAOYSA-N

Data: 2 IC50  4 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 54207   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Nucleotide-binding oligomerization domain-containing protein 2 (Homo sapiens (Human))	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.82E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R8T
					More data for this Ligand-Target Pair
Nucleotide-binding oligomerization domain-containing protein 1 (Homo sapiens (Human))	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	9.93E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CN72C0
					More data for this Ligand-Target Pair
Beta-2 adrenergic receptor (Homo sapiens (Human))	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.41E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: R03 MH093192-01 Project Title: HTS for Non-Canonical Ligands for Beta 2 Adrenergic Receptor...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2RB734K
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	6.72E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25M6443
					More data for this Ligand-Target Pair
Bcl-2-like protein 11 (Homo sapiens (Human))	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	6.26E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: apoptosis, BH3 domain, Bcl2-A1, BIM, caspase, cancer Primary Collaborator: Todd Golub, Broad Institute, golub@broadinstitute.org Assay Over...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q24J0CKJ
					More data for this Ligand-Target Pair
Heat shock factor protein 1 (Mus musculus)	BDBM54207 (MLS000538647 | N-[4-(3,4-dimethylphenyl)-5-methyl-...) Show SMILES Cc1sc(NC(=O)c2nn(C)cc2[N+]([O-])=O)nc1-c1ccc(C)c(C)c1 Show InChI InChI=1S/C17H17N5O3S/c1-9-5-6-12(7-10(9)2)14-11(3)26-17(18-14)19-16(23)15-13(22(24)25)8-21(4)20-15/h5-8H,1-4H3,(H,18,19,23)	PDB KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.28E+3	n/a	n/a	n/a	n/a
Broad Institute Curated by PubChem BioAssay					Assay Description Keywords: Heat Shock Factor-1 (HSF-1), Stress Response, MG132, NIH3T3, Luminescence Assay Overview: Modified NIH3T3, transformed to express firefly...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MW2FKX
					More data for this Ligand-Target Pair