BDBM54335 (5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-quinolinone::(5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]quinolin-8-one::(5E)-5-[(2,5-dimethylphenyl)hydrazono]quinolin-8-one::5-[(E)-(2,5-dimethylphenyl)diazenyl]quinolin-8-ol::MLS000681763::SMR000312806::cid_16194507

SMILES: Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12

InChI Key: InChIKey=PYMYOBKUNQPXCW-UHFFFAOYSA-N

Data: 4 IC50  1 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 54335   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
nucleotide-binding oligomerization domain containing 2 (Homo sapiens (Human))	BDBM54335 ((5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-qui...) Show SMILES Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12 |w:8.8| Show InChI InChI=1S/C17H15N3O/c1-11-5-6-12(2)15(10-11)20-19-14-7-8-16(21)17-13(14)4-3-9-18-17/h3-10,21H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	3.00E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q23R0R8T
					More data for this Ligand-Target Pair
nucleotide-binding oligomerization domain containing 1 (Homo sapiens (Human))	BDBM54335 ((5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-qui...) Show SMILES Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12 |w:8.8| Show InChI InChI=1S/C17H15N3O/c1-11-5-6-12(2)15(10-11)20-19-14-7-8-16(21)17-13(14)4-3-9-18-17/h3-10,21H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	4.12E+3	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CN72C0
					More data for this Ligand-Target Pair
Angiotensin II receptor (Homo sapiens (Human))	BDBM54335 ((5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-qui...) Show SMILES Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12 |w:8.8| Show InChI InChI=1S/C17H15N3O/c1-11-5-6-12(2)15(10-11)20-19-14-7-8-16(21)17-13(14)4-3-9-18-17/h3-10,21H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	9.84E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute(SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2CJ8BXT
					More data for this Ligand-Target Pair
Apelin receptor (Homo sapiens (Human))	BDBM54335 ((5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-qui...) Show SMILES Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12 |w:8.8| Show InChI InChI=1S/C17H15N3O/c1-11-5-6-12(2)15(10-11)20-19-14-7-8-16(21)17-13(14)4-3-9-18-17/h3-10,21H,1-2H3	PDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.73E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sanford-Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford- Sanford-Burnham Medical Research Institute(SBMRI, San...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2MK6BBZ
					More data for this Ligand-Target Pair
Tumor necrosis factor (Homo sapiens (Human))	BDBM54335 ((5E)-5-[(2,5-dimethylphenyl)hydrazinylidene]-8-qui...) Show SMILES Cc1ccc(C)c(c1)N=Nc1ccc(O)c2ncccc12 |w:8.8| Show InChI InChI=1S/C17H15N3O/c1-11-5-6-12(2)15(10-11)20-19-14-7-8-16(21)17-13(14)4-3-9-18-17/h3-10,21H,1-2H3	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	1.89E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q25M6443
					More data for this Ligand-Target Pair