BDBM54678 (3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylidene)-1H-indol-2-one::(3E)-7-bromo-3-(1-ketoindan-2-ylidene)oxindole::(3E)-7-bromo-3-(3-oxo-1H-inden-2-ylidene)-1H-indol-2-one::UNM-0000305764::cid_25220925

SMILES: Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O

InChI Key: InChIKey=GGXAOLJFFTZDJY-WYMLVPIESA-N

Data: 8 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 54678   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Ras-related protein Rab-2A. (Canis lupus familiaris)	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2V40SNS
					More data for this Ligand-Target Pair
cell division cycle 42 (GTP binding protein, 25kDa) (Homo sapiens (Human))	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q26H4FT9
					More data for this Ligand-Target Pair
cell division cycle 42 (GTP binding protein, 25kDa) (Homo sapiens (Human))	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB NCI pathway Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2Z31X2S
					More data for this Ligand-Target Pair
ras protein (Homo sapiens (Human))	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q23N21VG
					More data for this Ligand-Target Pair
ras protein (Homo sapiens (Human))	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2D21W1M
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mus musculus)	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q24M92ZV
					More data for this Ligand-Target Pair
Ras-related C3 botulinum toxin substrate 1 (Mus musculus)	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt UniProtKB/TrEMBL B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2W37TR5
					More data for this Ligand-Target Pair
GTP-binding protein (rab7) (Canis lupus familiaris)	BDBM54678 ((3E)-7-bromanyl-3-(3-oxidanylidene-1H-inden-2-ylid...) Show SMILES Brc1cccc2\C(C(=O)Nc12)=C1\Cc2ccccc2C1=O Show InChI InChI=1S/C17H10BrNO2/c18-13-7-3-6-11-14(17(21)19-15(11)13)12-8-9-4-1-2-5-10(9)16(12)20/h1-7H,8H2,(H,19,21)/b14-12+	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	n/a	n/a	3.00E+4	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH I RO3 MH081231-01 HTS to identify specific small molecule inhibitors of Ras and Ras-rela...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2X34VWJ
					More data for this Ligand-Target Pair