null

SMILES: COC(=O)N1[C@@H](C)CCc2c1ccc1n([C@H]3CC[C@@H](CC3)C(O)=O)c(Cc3ccc(OC(C)C)c(F)c3)nc21

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 547139   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Bromodomain-containing protein 4 (Homo sapiens (Human))	BDBM547139 (US11292791, Example 412) Show SMILES COC(=O)N1[C@@H](C)CCc2c1ccc1n([C@H]3CC[C@@H](CC3)C(O)=O)c(Cc3ccc(OC(C)C)c(F)c3)nc21 |r,wU:5.5,18.22,wD:15.15,(-6.09,-8.3,;-6.09,-6.76,;-4.76,-5.99,;-3.42,-6.76,;-4.76,-4.45,;-6.09,-3.68,;-7.43,-4.45,;-6.09,-2.14,;-4.76,-1.37,;-3.42,-2.14,;-3.42,-3.68,;-2.09,-4.45,;-.76,-3.68,;-.76,-2.14,;.39,-1.11,;1.87,-1.51,;2.27,-3,;3.76,-3.39,;4.85,-2.3,;4.45,-.82,;2.96,-.42,;6.34,-2.7,;7.43,-1.61,;6.74,-4.19,;-.24,.3,;.53,1.63,;-.24,2.97,;-1.78,2.97,;-2.55,4.3,;-1.78,5.63,;-2.55,6.97,;-4.09,6.97,;-4.86,8.3,;-4.86,5.63,;-.24,5.63,;.53,6.97,;.53,4.3,;-1.77,.14,;-2.09,-1.37,)| Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	550	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SQM
					More data for this Ligand-Target Pair
CREB-binding protein (Homo sapiens (Human))	BDBM547139 (US11292791, Example 412) Show SMILES COC(=O)N1[C@@H](C)CCc2c1ccc1n([C@H]3CC[C@@H](CC3)C(O)=O)c(Cc3ccc(OC(C)C)c(F)c3)nc21 |r,wU:5.5,18.22,wD:15.15,(-6.09,-8.3,;-6.09,-6.76,;-4.76,-5.99,;-3.42,-6.76,;-4.76,-4.45,;-6.09,-3.68,;-7.43,-4.45,;-6.09,-2.14,;-4.76,-1.37,;-3.42,-2.14,;-3.42,-3.68,;-2.09,-4.45,;-.76,-3.68,;-.76,-2.14,;.39,-1.11,;1.87,-1.51,;2.27,-3,;3.76,-3.39,;4.85,-2.3,;4.45,-.82,;2.96,-.42,;6.34,-2.7,;7.43,-1.61,;6.74,-4.19,;-.24,.3,;.53,1.63,;-.24,2.97,;-1.78,2.97,;-2.55,4.3,;-1.78,5.63,;-2.55,6.97,;-4.09,6.97,;-4.86,8.3,;-4.86,5.63,;-.24,5.63,;.53,6.97,;.53,4.3,;-1.77,.14,;-2.09,-1.37,)| Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	5.5	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description The assay was performed in a final volume of 6 μL in assay buffer containing 50 mM Hepes (pH 7.5, (0.5M Hepes, pH 7.5 solution; Teknova H1575)),...				Citation and Details BindingDB Entry DOI: 10.7270/Q2MG7SQM
					More data for this Ligand-Target Pair