BDBM54714 3-chloranyl-4-[(1,5-dimethyl-3-oxidanylidene-2-phenyl-pyrazolidin-4-yl)amino]-1-(4-methoxyphenyl)pyrrole-2,5-dione::3-chloro-4-[(1,5-dimethyl-3-oxo-2-phenyl-4-pyrazolidinyl)amino]-1-(4-methoxyphenyl)pyrrole-2,5-dione::3-chloro-4-[(1,5-dimethyl-3-oxo-2-phenylpyrazolidin-4-yl)amino]-1-(4-methoxyphenyl)pyrrole-2,5-dione::3-chloro-4-[(3-keto-1,5-dimethyl-2-phenyl-pyrazolidin-4-yl)amino]-1-(4-methoxyphenyl)-3-pyrroline-2,5-quinone::UNM-0000306189::cid_44203217

SMILES: COc1ccc(cc1)-n1c(O)c(Cl)c(Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1O

InChI Key: InChIKey=JUWZGBQVKTZVRP-UHFFFAOYSA-N

Data: 3 EC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 54714   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Apoptosis regulator Bcl-B (Bcl-2-like 10 protein) (Bcl2-L-10) (Anti-apoptotic protein NrH). (Homo sapiens (Human))	BDBM54714 (3-chloranyl-4-[(1,5-dimethyl-3-oxidanylidene-2-phe...) Show SMILES COc1ccc(cc1)-n1c(O)c(Cl)c(Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C22H21ClN4O4/c1-13-18(22(30)27(25(13)2)15-7-5-4-6-8-15)24-19-17(23)20(28)26(21(19)29)14-9-11-16(31-3)12-10-14/h4-12,24,28-29H,1-3H3	PDB KEGG B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	620	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2NG4P21
					More data for this Ligand-Target Pair
Induced myeloid leukemia cell differentiation protein Mcl-1 (Homo sapiens (Human))	BDBM54714 (3-chloranyl-4-[(1,5-dimethyl-3-oxidanylidene-2-phe...) Show SMILES COc1ccc(cc1)-n1c(O)c(Cl)c(Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C22H21ClN4O4/c1-13-18(22(30)27(25(13)2)15-7-5-4-6-8-15)24-19-17(23)20(28)26(21(19)29)14-9-11-16(31-3)12-10-14/h4-12,24,28-29H,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	540	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q24F1P57
					More data for this Ligand-Target Pair
Bcl-2-related protein A1 (Homo sapiens (Human))	BDBM54714 (3-chloranyl-4-[(1,5-dimethyl-3-oxidanylidene-2-phe...) Show SMILES COc1ccc(cc1)-n1c(O)c(Cl)c(Nc2c(C)n(C)n(-c3ccccc3)c2=O)c1O Show InChI InChI=1S/C22H21ClN4O4/c1-13-18(22(30)27(25(13)2)15-7-5-4-6-8-15)24-19-17(23)20(28)26(21(19)29)14-9-11-16(31-3)12-10-14/h4-12,24,28-29H,1-3H3	PDB MMDB NCI pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	PCBioAssay	n/a	n/a	n/a	n/a	1.24E+3	n/a	n/a	n/a	n/a
NMMLSC Curated by PubChem BioAssay					Assay Description University of New Mexico Assay Overview: Assay Support: NIH 1X01 MH079850-01 HTS to identify small molecule regulators of Bcl-2 family protein int...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2HQ3XCR
					More data for this Ligand-Target Pair