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SMILES: CC(C)(C)c1cccc(n1)-n1n(CC(F)(F)F)c(=O)c2cnc(Nc3ccc4CCNCc4c3)nc12

InChI Key:

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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 549236   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Wee1-like protein kinase


(Homo sapiens (Human))		BDBM549236
PNG
(US11299493, Compound 1.152 | US11299493, S-55)
Show SMILES CC(C)(C)c1cccc(n1)-n1n(CC(F)(F)F)c(=O)c2cnc(Nc3ccc4CCNCc4c3)nc12
PDB
MMDB

NCI pathway
Reactome pathway
KEGG

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US Patent
n/an/a<1n/an/an/an/an/an/a


TBA

Assay Description
IC50 values of compounds against WEE1 kinase enzyme were determined by LanthaScreen Terbium Labeled TR-FRET assay. Kinase assays were performed in 1×...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2P84G37
More data for this
Ligand-Target Pair