BDBM55037 3-(5-{[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl}-2-furyl)-4-methylbenzoic acid::3-[5-[(Z)-[2,4-bis(oxidanylidene)-3-(2-oxidanylidene-2-phenylazanyl-ethyl)-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-4-methyl-benzoic acid::3-[5-[(Z)-[3-(2-anilino-2-keto-ethyl)-2,4-diketo-thiazolidin-5-ylidene]methyl]-2-furyl]-4-methyl-benzoic acid::3-[5-[(Z)-[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thiazolidin-5-ylidene]methyl]furan-2-yl]-4-methylbenzoic acid::3-[5-[(Z)-[3-(2-anilino-2-oxoethyl)-2,4-dioxo-5-thiazolidinylidene]methyl]-2-furanyl]-4-methylbenzoic acid::MLS000705088::SMR000231712::cid_1232170

SMILES: Cc1ccc(cc1-c1ccc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3)C2=O)o1)C(O)=O

InChI Key: InChIKey=WTPQFTZEPOVIPL-NDENLUEZSA-N

Data: 4 IC50

Find this compound or compounds like it in BindingDB or PDB:

Substructure Similarity at least:  must be >=0.5 Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 55037   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
NS3 (Hepatitis C virus)	BDBM55037 (3-(5-{[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thia...) Show SMILES Cc1ccc(cc1-c1ccc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3)C2=O)o1)C(O)=O Show InChI InChI=1S/C24H18N2O6S/c1-14-7-8-15(23(29)30)11-18(14)19-10-9-17(32-19)12-20-22(28)26(24(31)33-20)13-21(27)25-16-5-3-2-4-6-16/h2-12H,13H2,1H3,(H,25,27)(H,29,30)/b20-12-	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	5.39E+3	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Molecular Screening Center Curated by PubChem BioAssay					Assay Description Source (MLPCN Center Name): The Scripps Research Institute Molecular Screening Center (SRIMSC) Center Affiliation: The Scripps Research Institute (TS...				PubChem Bioassay (2009) BindingDB Entry DOI: 10.7270/Q2XS5ST3
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM55037 (3-(5-{[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thia...) Show SMILES Cc1ccc(cc1-c1ccc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3)C2=O)o1)C(O)=O Show InChI InChI=1S/C24H18N2O6S/c1-14-7-8-15(23(29)30)11-18(14)19-10-9-17(32-19)12-20-22(28)26(24(31)33-20)13-21(27)25-16-5-3-2-4-6-16/h2-12H,13H2,1H3,(H,25,27)(H,29,30)/b20-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+5	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of PGES-1 in human whole blood assessed as LPS-induced PGE2 formation incubated for 15 mins prior to LPS addition measured after 24 hrs by...				J Med Chem 56: 3296-309 (2013) Article DOI: 10.1021/jm301900x BindingDB Entry DOI: 10.7270/Q2TB188S
					More data for this Ligand-Target Pair
Prostaglandin E synthase (Homo sapiens (Human))	BDBM55037 (3-(5-{[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thia...) Show SMILES Cc1ccc(cc1-c1ccc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3)C2=O)o1)C(O)=O Show InChI InChI=1S/C24H18N2O6S/c1-14-7-8-15(23(29)30)11-18(14)19-10-9-17(32-19)12-20-22(28)26(24(31)33-20)13-21(27)25-16-5-3-2-4-6-16/h2-12H,13H2,1H3,(H,25,27)(H,29,30)/b20-12-	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
Peking University Curated by ChEMBL					Assay Description Inhibition of full-length microsomal PGES-1 (unknown origin) expressed in Escherichia coli Rosetta(DE3) using PGH2 as substrate assessed as inhibitio...				J Med Chem 56: 3296-309 (2013) Article DOI: 10.1021/jm301900x BindingDB Entry DOI: 10.7270/Q2TB188S
					More data for this Ligand-Target Pair
carboxy-terminal domain RNA polymerase II polypeptide A small phosphatase 1 isoform 1 (Homo sapiens (Human))	BDBM55037 (3-(5-{[3-(2-anilino-2-oxoethyl)-2,4-dioxo-1,3-thia...) Show SMILES Cc1ccc(cc1-c1ccc(\C=C2/SC(=O)N(CC(=O)Nc3ccccc3)C2=O)o1)C(O)=O Show InChI InChI=1S/C24H18N2O6S/c1-14-7-8-15(23(29)30)11-18(14)19-10-9-17(32-19)12-20-22(28)26(24(31)33-20)13-21(27)25-16-5-3-2-4-6-16/h2-12H,13H2,1H3,(H,25,27)(H,29,30)/b20-12-	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	PCBioAssay	n/a	n/a	2.75E+3	n/a	n/a	n/a	n/a	n/a	n/a
Burnham Center for Chemical Genomics Curated by PubChem BioAssay					Assay Description Data Source: Sanford-Burnham Center for Chemical Genomics (SBCCG) Source Affiliation: Sanford-Burnham Medical Research Institute (SBMRI, San Diego, C...				PubChem Bioassay (2011) BindingDB Entry DOI: 10.7270/Q2V986KM
					More data for this Ligand-Target Pair