null
SMILES: Oc1ccc(O)n1-c1ccc(NC(=O)c2ccccn2)cc1Cl
InChI Key: InChIKey=OFMVUKRZXRBAPP-UHFFFAOYSA-N
Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kcal/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM55085 (N-(3-chloro-4-succinimido-phenyl)picolinamide | N-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 5.96E+3 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2VT1QHF | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 (Homo sapiens (Human)) | BDBM55085 (N-(3-chloro-4-succinimido-phenyl)picolinamide | N-...) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | Article PubMed | n/a | n/a | n/a | n/a | 6.20E+3 | n/a | n/a | n/a | n/a |
Vanderbilt University Medical Center Curated by ChEMBL | Assay Description Positive allosteric modulator activity at human mGlu4 receptor expressed in CHO cells expressing Gqi5 by calcium mobilization assay | J Med Chem 54: 7639-47 (2011) Article DOI: 10.1021/jm200956q BindingDB Entry DOI: 10.7270/Q25Q4WHD | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Metabotropic glutamate receptor 4 [Q124R] (Rattus norvegicus) | BDBM55085 (N-(3-chloro-4-succinimido-phenyl)picolinamide | N-...) | PDB KEGG UniProtKB/SwissProt GoogleScholar AffyNet | PC cid PC sid UniChem Patents Similars | PCBioAssay | n/a | n/a | n/a | n/a | 6.89E+3 | n/a | n/a | n/a | n/a |
Vanderbilt Screening Center for GPCRs, Ion Channels and Transporters Curated by PubChem BioAssay | Assay Description Assay Provider: Colleen Niswender Assay Provider Affiliation: Vanderbilt University The primary pathophysiological change giving rise to the symptoms... | PubChem Bioassay (2010) BindingDB Entry DOI: 10.7270/Q2DR2SWV | |||||||||||
More data for this Ligand-Target Pair |