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SMILES: NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1C2CC3CC(C2)CC1C3)n1cc(nn1)C1CC1

InChI Key:

Find this compound or compounds like it in BindingDB or PDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 552693   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kcal/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
von Hippel-Lindau disease tumor suppressor


(Homo sapiens (Human))		BDBM552693
PNG
((2S,4R)-N-((R)-3-([l,l'-biphenyl]-4-yl)-l-amino-l-...)
Show SMILES NC(=O)[C@@H](Cc1ccc(cc1)-c1ccccc1)NC(=O)C1C[C@@H](O)CN1C(=O)[C@H](C1C2CC3CC(C2)CC1C3)n1cc(nn1)C1CC1 |wU:3.18,22.24,wD:28.44,TLB:28:29:31:33.34.35,THB:33:32:29:34.35.36,33:34:29:31.32.38,36:34:31:29.37.38,36:37:31:33.34.35,(-6.74,-5.5,;-8.1,-4.77,;-9.41,-5.57,;-8.14,-3.23,;-9.5,-2.5,;-10.81,-3.3,;-10.76,-4.84,;-12.07,-5.65,;-13.43,-4.92,;-13.47,-3.38,;-12.16,-2.57,;-14.74,-5.73,;-14.69,-7.27,;-16.01,-8.08,;-17.36,-7.34,;-17.4,-5.81,;-16.09,-5,;-6.83,-2.42,;-5.47,-3.15,;-5.43,-4.69,;-4.16,-2.34,;-4.05,-.81,;-2.55,-.44,;-1.96,.98,;-1.74,-1.75,;-2.74,-2.93,;-2.37,-4.42,;-3.49,-5.49,;-.9,-4.86,;.22,-3.79,;1.59,-3.1,;2.96,-3.79,;3.8,-2.32,;3.8,-.92,;2.43,-.23,;1.59,-1.7,;1.06,-.92,;1.06,-2.32,;2.43,-3.02,;-.53,-6.35,;.89,-6.94,;.77,-8.47,;-.72,-8.84,;-1.53,-7.53,;1.95,-9.47,;3.46,-9.75,;2.47,-10.92,)|
PDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
WIPO WO2022103411
n/an/a 120n/an/an/an/an/an/a


TBA

Assay Description
The VHL NanoBRET™ Target Engagement Assay analyzes the apparent affinity of test compounds for VHL in cells by competitive displacement of a VHL Nano...

Citation and Details

BindingDB Entry DOI: 10.7270/Q2WM1HMJ
More data for this
Ligand-Target Pair