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SMILES: CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1

InChI Key:

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 553953   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kcal/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Poly [ADP-ribose] polymerase 1 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	PDB MMDB UniProtKB/SwissProt B.MOAD antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7	n/a	n/a	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase 2 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	3.30E+3	n/a	n/a	n/a	n/a	n/a	n/a
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Potassium voltage-gated channel subfamily H member 2 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	>4.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Poly [ADP-ribose] polymerase tankyrase-1 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	6.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein mono-ADP-ribosyltransferase PARP6 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	3.10E+4	n/a	n/a	n/a	n/a	n/a	n/a
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Protein mono-ADP-ribosyltransferase PARP3 (Homo sapiens (Human))	BDBM553953 (US11325906, Example 16) Show SMILES CNC(=O)c1ccc(N2CCN(Cc3ccc4nc(c(=O)[nH]c4c3)C(F)(F)F)CC2)c(Cl)n1 Show InChI	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem		n/a	n/a	7.40E+4	n/a	n/a	n/a	n/a	n/a	n/a
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